Zeynep Burçin Gönen, DDS, PhD, Assoc. Prof.
Oral & Maxillofacial Surgery and Immunology
Erciyes University,
Genome and Stem Cell Center (GENKOK)
Dr. Zeynep Burçin GONEN received her DDs degree and graduated with an honour degree from Faculty of Dentistry, Ondokuz Mayıs University (Turkey). She trained in the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Erciyes University, Kayseri, Turkey; and received her specialization and PhD degree in Oral and Maxillofacial Surgery (OMFS). She had Immunology MSC degree from the same university.
Dr. Gonen trained for facial plastic surgery at Facial Plastic Surgery and OMFS department at Poole Hospital NHS, UK,. She had Associate Professor Degree in Oral and Maxillofacial Surgery in 2019. Dr. Gonen is Director of mesenchymal stem cell production unit of Erciyes University, Genome and Stem Cell Center (GENKÖK) since 2014. She is a member of Cell Therapy and Immunology Group at the Turkish Health Institutes of Turkey.
Dr. Gonen is one of the representatives of NEXTGEN-Europe in International Association of Oral and Maxillofacial Surgeons (IAOMS).
EDUCATION
2007-2013 Residency Specialty Training including PhD, Department of Oral and Maxillofacial Surgery, Erciyes University, Kayseri, Turkey. PhD Thesis: Evaluation of Vestibular Bone Thickness in Class I Malocclusion Treatment with Corticotomy Assisted Rapid Orthodontics Supervisor: Prof. Alper ALKAN
2002-2007 Faculty of Dentistry Ondokuz Mayıs University, Samsun, Turkey
1995-2002 Anadolu College, Amasya, Turkey (5.0/ 5.0)
QUALIFICATIONS
Associate Professorship: 2019 Oral and Maxillofacial Surgery, Interuniversity Board of Turkey
Specialist: 2014 Oral and Maxillofacial Surgery, Turkish Health of Ministry
PhD: 2013 Department of Oral and Maxillofacial Surgery, Institute of Health, Erciyes University, Kayseri, Turkey
DDS: 2007 Faculty of Dentistry, Ondokuz Mayıs University, Samsun, Turkey
Rotations in Training
2009 Department of Anesthesiology and Reanimation, Faculty of Medicine, Erciyes University, Kayseri, Turkey (2 months)
2010 Department of Otorhinolaryngology, Faculty of Medicine, Erciyes University, Kayseri, Turkey (3 months)
2011 Department of Emergency, Faculty of Medicine, Erciyes University, Kayseri, Turkey (2 months)
International Experience
2006-2007 Vilnius University, Medical Faculty, Institute of Odontology, Vilnius, Lithuania (6 months)
2017 Honorary Observership/ Fellowship in Facial Plastic Surgery, Oral and Maxillofacial Surgery, 5 Jun -7 Aug, Poole Hospital NHS, United Kingdom (Prof V. Ilankovan, 2 months)
2020 Fellowship in Facial Plastic Surgery, Oral and Maxillofacial Surgery, 20 February 2020 – 19 August 2020, Poole Hospital NHS, United Kingdom (Prof V. Ilankovan, 6 months)
CURRENT POSITIONS
2014-ongoing Assistant Professor (PhD Teaching Staff), Erciyes University, Kayseri, TR
2014- ongoing Vice Director, Genome and Stem Cell Center, Erciyes University
2015- ongoing Production Manager of GMP laboratory, Stem Cell Unit, Erciyes University
Committee Positions
2014-ongoing Occupational Health and Safety Committee, Member, Erciyes University
2017-ongoing Infection Control Committee, President, Genome and Stem Cell Center
2017-ongoing Turkish National Institutes of Health (TÜSEB), Cancer Institute, Immunology and Cellular Therapy Group, Member, Ankara, Turkey
2018-ongoing Quality Control Committee, Member, Erciyes University, Kayseri, Turkey
2018-ongoing Social and Cultural Events Committee, President, Genome and Stem Cell Center
2018-ongoing Turkish Academy of Sciences (TÜBA), Working Group of Stem Cell, Member, Ankara, Turkey
EMPLOYMENT HISTORY
2007-2013 Resident, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Erciyes University, Kayseri, Turkey
2010- ongoing Private Practice, Kayseri, TR (part time)
2014-2016 Oral and Maxillofacial Surgeon, Hospitadent International Dental Hospital, Kayseri, TR (part time)
AWARDS
Honors Graduate 2007 Ondokuz Mayıs University, Samsun, Turkey
Valedictorian 2007 Faculty of Dentistry, Ondokuz Mayıs University, Samsun, TR
PRIZES
2014 Oral Presentation of Young Doctors award, 11th Asian Congress on Oral and Maxillofacial Surgery, ‘’Evaluation of Vestibular Bone Thickness in Class I Malocclusion Treatment with Corticotomy Assisted Rapid Orthodontics ‘’, XIAN, China
2014 Oral presentation award, International Congress of Oral and Maxillofacial Surgery Society (ACBID) ‘’Stem Cell Application in Alveolar Cleft: An Experimental Study’’, Antalya, Turkey
2014 Best Poster Award, BAOMS-ACBID Joint Congress (British Association Oral and Maxillofacial Surgeons and Oral and Maxillofacial Surgery Society), ‘’ Apical Papilla Stem Cells from Supernumerary Tooth and Comparative Characterization with Wisdom Tooth ‘’ İstanbul, Turkey
2015 Best Poster award, International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), “Evaluation of the Effect of Ankaferd on Dental Pulp Derived Mesenchymal Stem Cells and Gingival Fibroblasts” Antalya, Turkey
2015 Oral Presentation Award (Third Place), International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), ‘’Evaluation of the Effect of Photoionization on Dental Implant Osseointegration: Experimental Study’’ Antalya, Turkey
2016 Best Oral Presentation Award, International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), ‘’ Exosomes Secreted from Dental Pulp Mesenchymal Stem Cells Promote Repair and Regeneration of Temporomandibular Joint in Osteoarthritis’’. Antalya, Turkey
2017 Dogsan Science Award, Turkish Society of Plastic-Reconstructive and Esthetics Surgeons (Second Place in Research Category), ‘’ Effect of Mesenchymal Stem Cells in Sciatic Nerve Repair: Functional, Electrophysiological and Histomorphometric and Immunohistochemically Analysis’ ’Antalya, Turkey
2018 Innovative Dentist of the Year’ DoktorClub Award, Turkey
2021 Science Award, Turkish Society of Plastic-Reconstructive and Esthetics Surgeons (First Place in Research Category), ‘’ 3D Chitosan-Heparin Tissue Scaffold with Mesenchymal Stem Cells for chondrogenesis: in vitro and in vivo study’ ’Antalya, Turkey
COURSES GIVEN
RESEARCH GRANTS OBTAINED
Competitive research grants from public funding authorities
Competitive research grants from the Scientific Research Support Division of University
INVITED LECTURES
PUBLICATIONS
A. Articles Published in International Refereed Journals *Surname was changed to ‘Gonen’ in 2010.
A1. Turgut M, Kaplan S, Unal BZ, Bozkurt M, Yürüker S, Yenisey C, Sahin B, Uyanıkgil Y, Baka M. Stereological analysis of sciatic nerve in chickens following neonatal pinealectomy: an experimental study. J Brachial Plex Peripher Nerve Inj. 2010 Apr 21;5:10.
A2. Çelebi N, Gönen ZB, Kılıç E, Etöz OA, Alkan A. Maxillary Sinus Floor Augmentation in Patients with Maxillary Sinus Pseudocyst: Case Report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Dec;112(6): 97-102.
A3. Kılıç E, Gönen ZB, Alkan A. Osteonecrosis related to oral bisphosphonate usage: case report and review of treatment strategies. J Int Dent Med Res 5(1): 45-48 (2012)
A4. Kütük N, Demirbaş AE, Gönen ZB, Topan C, Kiliç E, Etöz OA, Alkan A. Anterior mandibular zone safe for implants. J Craniofac Surg. 2013 Jul;24(4): 405-8
A5. Kütük N, Baş B, Soylu E, Gönen ZB, Yilmaz C, Balcioğlu E, Özdamar S, Alkan A. Effect of platelet rich plasma (PRP) on fibrocartilage, hyaline cartilage and bone repair in temporomandibular joint. J Oral Maxillofac Surg. 2014 Feb;72(2):277-84
A6. Kütük N, Gönen ZB, Yaşar MT, Demirbaş AE, Alkan A. Reliability of panoramic radiography in determination of neurosensory disturbances related to dental implant placement in posterior mandible. Implant Dent. 2014 Dec;23(6):648-52.
A7. Ozcan S, Alessio N, Acar B, Toprak G, Gonen ZB, Peluso G, Galderisi U. Myeloma cells can corrupt senescent mesenchymal stromal cells and impair their anti-tumor activity. Oncotarget. 2015 Nov 24;6(37):39482-92.
A8. Oner A, Gonen ZB, Sinim N, Cetin M, Ozkul Y. Subretinal adipose tissue-derived mesenchymal stem cell implantation in advanced stage retinitis pigmentosa: a phase I clinical safety study. Stem Cell Res Ther. 2016 1;7(1):178.
A9. Abbas OL, Borman H, Uysal ÇA, Gönen ZB, Aydin L, Helvacioğlu F, Ilhan Ş, Yazici AC. Adipose-Derived Stem Cells Enhance Axonal Regeneration through Cross-Facial Nerve Grafting in a Rat Model of Facial Paralysis. Plast Reconstr Surg. 2016 Aug;138(2):387-96.
A10. Gönen ZB, Yılmaz Asan C, Etöz O, Alkan A. Oral leukoplakia associated with amalgam restorations. J Oral Sci. 2016;58(3):445-8.
A11. Ozcan G, Sekerci AE, Gönen ZB. Are there any differences in mandibular morphology of patients with bisphosphonate-related osteonecrosis of jaws?: a case-control study. Dentomaxillofac Radiol. 2016 Jun 1:20160047l.
A12. Canpolat DG, Dogruel F, Gönen ZB, Yılmaz C, Zararsız G, Alkan A. The role of platelet count, mean platelet volume, and the mean platelet volume/platelet count ratio in predicting postoperative vomiting in children after deep sedation. Saudi Med J. 2016 Oct;37(10):1082-8.
A13. Kaynar L, Demir K, Turak EE, Öztürk ÇP, Zararsız G, Gönen ZB, Gökahmetoğlu S, Şıvgın S, Eser B, Köker Y, Solmaz M, Ünal A, Çetin M. TcRαβ-depleted haploidentical transplantation results in adult acute leukemia patients. Hematology. 2017;22(3):136-144.
A14. Gönen ZB, Yılmaz Asan C. Treatment of bisphosphonate-related osteonecrosis of the jaw using platelet-rich fibrin. Cranio. 2017 Sep;35(5):332-336.
A15. Sayan A, Gonen ZB, Ilankovan V. Multiple metastases to bone from squamous cell carcinoma of the oropharynx: unusual findings on positron emission tomography-computed tomography. Br J Oral Maxillofac Surg. 2017 ;55(10):1044-1045.
A16. Cetin M, Akyol G, Gonen ZB, Keklik M, Zararsiz G, Unal A, Tiren-Verbeet NL, Kaynar L. Additional infusions of mesenchymal stem cells improve response rate in multidrug-resistant GvHD patients. Bone Marrow Transplant. 2017 ;52(5):783-785.
A17. Keni N, Kaynar L, Ünal A, Demir K, Ermis Turak E, Gönen ZB, Şıvgın S, Eser B, Ünal A, Çetin M. Transplantation of Single Mismatch Hematopoietic Stem Cells with Third Party Mesenchymal Stem Cells for Severe Aplastic Anemia: A Case Report and Mini Review. Ann Hematol Oncol. 2017; 4(5): 1150.
A18. Dogruel F, Gonen ZB, Gunay-Canpolat D, Zararsiz G, Alkan A. The Neutrophil-to-Lymphocyte ratio as a marker of recovery status in patients with severe dental infection. Med Oral Patol Oral Cir Bucal. 2017 Jul 1;22(4): 440-445.
A19. Soylu E, Gönen ZB, Alkan A. A New Detection Method for Submerged Implants: Oral Tattoo. J Prosthodont. 2018 Apr;27(4):361-363.
A20. Gönen ZB, Yillmaz Asan C, Zararsiz G, Kiliç E, Alkan A. Osseous changes in patients with medication - related osteonecrosis of the jaws. Dentomaxillofac Radiol 2018; 47(1):20170172.
A21. Abbas OL, Özatik O, Gönen ZB, Öğüt S, Özatik FY, Salkın H, Musmul A. Comparative Analysis of Mesenchymal Stem Cells from Bone Marrow, Adipose Tissue, and Dental Pulp as Sources of Cell Therapy for Zone of Stasis Burns. J Invest Surg 2019;32(6):477-490.
A22. Şahiner M, Bahar D, Öner A, Gönen ZB, Ünlü M, Gülmez Sevim D, Karaca Ç, Mirza GE. The Effects of Anti-Vascular Endothelial Growth Factor Drugs on Retinal Pigment Epithelial Cell Culture. Turk J Ophthalmol. 2018 Aug;48(4):190-195.
A23. Abbas OL, Özatik O, Gönen ZB, Öğüt S, Entok E, Özatik FY, Bahar D, Bakir ZB, Musmul A. Prevention of Burn Wound Progression by Mesenchymal Stem Cell Transplantation: Deeper Insights Into Underlying Mechanisms. Ann Plast Surg. 2018 Dec;81(6):715-724.
A24. Çolpak HA, Gönen ZB, Özdamar S, Alkan A, Kütük N. Vertical ridge augmentation using guided bone regeneration procedure and dental pulp derived mesenchymal stem cells with simultaneous dental implant placement: A histologic study in a sheep model. J Stomatol Oral Maxillofac Surg. 2019;120(3):216-223.
A25. Yazan M, Kocyigit ID, Atil F, Tekin U, Gonen ZB, Onder ME. Effect of hyaluronic acid on the osseointegration of dental implants. Br J Oral Maxillofac Surg. 2019;57(1):53-57.
A26. Dogruel F, Gonen ZB, Canpolat DG, Ocak H, Bayram F. Investigation of Vitamin D levels in medical staff in a dental clinic. Niger J Clin Pract. 2019;22(4):573-577.
A27. Abbas OL, Özatik O, Gönen ZB, Koçman AE, Dağ I, Özatik FY, Bahar D, Musmul A. Bone Marrow Mesenchymal Stem Cell Transplantation Enhances Nerve Regeneration in a Rat Model of Hindlimb Replantation. Plast Reconstr Surg. 2019;143(4):758-768.
A28. Oner A, Gonen ZB, Sevim DG, Smim Kahraman N, Unlu M. Suprachoroidal Adipose Tissue-Derived Mesenchymal Stem Cell Implantation in Patients with Dry-Type Age-Related Macular Degeneration and Stargardt's Macular Dystrophy: 6-Month Follow-Up Results of a Phase 2 Study. Cellular Reprogramming Vol. 20, No. 6 Dec 2018.ahead of print http://doi.org/10.1089/cell.2018.0045.
A29. Salkın H, Gönen ZB, Ergen E, Bahar D, Çetin M. Effects of TGF-β1 Overexpression on Biological Characteristics of Human Dental Pulp-derived Mesenchymal Stromal Cells. Int J Stem Cells 2019;12(1):170-182.
A30. Gonen ZB, Colpak HA, Onger ME. Effects of Bisphosphonate Treatment on Mandibular Condyle Tissues of Temporomandibular Joint: A Stereological Study. J Stomatol Oral Maxillofac Surg. 2019;120(6):513-516.
A31. Mercan U, Gonen ZB, Salkin H, Yalcin Ulker GM, Meral DG. Comparison of the effect of postoperative care agents on human gingival fibroblasts: a preliminary study. Eur Oral Res. 2019;53(2):67-73.
A32. Oner A, Gonen ZB, Sevim DG, Sinim Kahraman N, Unlu M. Six-month results of suprachoroidal adipose tissue-derived mesenchymal stem cell implantation in patients with optic atrophy: a phase 1/2 study. Int Ophthalmol. 2019;39(12):2913-2922.
A33. Gonen ZB, Alkan A, Ekizer A, Kutuk N, Tasdemir Z. Evaluation of Vestibular Bone Thickness in Class I Malocclusion Treatment With Corticotomy-Assisted Rapid Orthodontics. J Craniofac Surg. 2019;30(8):727-733.
A34. Salkın H, Gönen ZB, Özcan S, Bahar D, Lekesizcan A, Taheri S, Kütük N, Alkan A. Effects of combination TGF-B1 transfection and platelet rich plasma (PRP) on three-dimension chondrogenic differentiation of rabbit dental pulp-derived mesenchymal stem cells. Connect Tissue Res. 2021 Mar;62(2):226-237.
A35. Olçar HA, Halıcı M, Kafadar İH, Karaman İ, Lekesizcan A, Gönen ZB. Can injection of adipose stem cells to non-union zone increase bone union? Experimental rat study. Jt Dis Relat Surg. 2020;31(1):20-27.
A36. Sayan A, Coftas R, Gonen ZB, Ilankovan V. Head and neck/maxillofacial nurse-led clinical activity during COVID-19 Pandemic - experience of one unit [published online ahead of print, 2020 Aug 3]. Br J Oral Maxillofac Surg. 2020;S0266-4356(20)30376-4.
A37. Uzun E, Güney A, Gönen ZB, Özkul Y, Kafadar İH, Günay M, Mutlu M. Intralesional allogeneic adipose-derived stem cells application in chronic diabetic foot ulcer: Phase I/2 safety study [published online ahead of print, 2020 Aug 13]. Foot Ankle Surg. 2020;S1268-7731(20)30169-7.
A38. Goh M, Gönen ZB, Sayan A, Ilankovan V. Evolution of surgical modalities in the management of rhinophyma: our experience. Br J Oral Maxillofac Surg. 2021 Feb;59(2):222-227.
A39. Sayan A, Gonen ZB, Ilankovan V. Adverse reactions associated with perioral rejuvenation using laser, fat and hyaluronic acid: systematic review. Br J Oral Maxillofac Surg. 2021 Nov;59(9):1005-1012.
A40. Kemaloğlu CA, Özyazgan İ, Gönen ZB. Immediate fat and nanofat-enriched fat grafting in breast reduction for scar management. J Plast Surg Hand Surg. 2021 Jun;55(3):173-180.
B. Articles Published in National Refereed Journals
B1. Turgut M, Kaplan S, Ünal ZB, Altunkaynak Z, Ünal D, Şahin B, Bozkurt M, Yurtseven ME. Effects of Pinealectomy on Morphological Features of Blood Vessel in Chicken: An Electron Mıcroscopıc and Stereologıcal Study. J Experiment and Clin Med 2009; 29(3):112-118.
B2. Çelebi N, Soylu E, Gönen ZB, Etöz O, Kiliç E, Alkan A. Retrospective Evaluation of Dental Implant Success: Three to Five Years Follow Up. Cumhuriyet Dent J. 16(1), 20-24 (2013)
B3. Çelebi N, Gönen ZB, Alkan A. Massive Odontogenic Cyst Deviating Nasal and Maxillary Sinus Floor. Journal of Health Sciences, 22(1), 99-101 (2013)
B4. Etöz O, Gönen ZB, Deniz K, Alkan A. Pleomorphic Adenoma in Upper Lip Mucosa: A Clinical Report. Cumhuriyet Dent J 16 (3): 213-216, 2013.
B5. Etöz OA, Gönen ZB, Akçay H, Günhan Ö, Alkan A. Odontogenic Myxoma of the Maxilla with Soft Tissue Involvement: Case Report. Turkish Clinics J Dental Sci 2014;20(3):191-4.
B6. Demetoglu U, Gönen ZB, Asan C, Kılıç E, Alkan A. An Impacted Ectopic Wisdom Tooth that Caused Pulpitis Pain on the Second Molar: A Case Report. Journal of Health Sciences 2015; 24: 120-123.
B7. Gönen ZB, Asan C, Kütük N, Alkan A. Unilateral Facial Nerve Paralysis Caused by Dental Infection. J Dent Fac Atatürk Uni. Supplement: 14, 2016: 32-36
B8. Gönen ZB, Soylu E, Akbulut N. Stem Cell Applications in Oral and Maxillofacial Surgery. Turkish Clinics J Oral Maxillofac Surg-Special Topics 2016;2(2) :36-41
B9. Soylu E, Gönen ZB, Akbulut N. Biomedical Approach to Tissue Engineering in Maxillofacial Surgery and Applications. Turkish Clinics J Oral Maxillofac Surg-Special Topics 2016;2(2) :48-52.
B10. Ekizer A, Gonen ZB, Topsakal KG. Biomechanics and Disorders of Temporomandibular Joint. Turkish Clinics J Orthod-Special Topics 2016;2(2):9-17.
B11. Gonen ZB. The Evaluation of Electroporation Parameters for Dental Pulp Mesenchymal Stem Cells. Journal of Health Sciences. 2016; 25: 144-147.
B12. Canpolat D, Gönen ZB, Durdu T. Evaluation of Approaches of the Dentists to General Anesthesia in the Clinical Practice. J Dent Fac Atatürk Uni. 2016, 26 (3): 389-393.
B13. Canpolat D, Gönen ZB, Dogruel F, Şengül İ, Yıldız K. Determination of Cardiopulmonary Resuscitation Knowledge Level of Dentists. Gaziantep Medical Journal 2016;22(4):197-201
B14. Gönen ZB, Doğruel F, Yılmaz Asan C, Kaynar L, Çetin M Short-term danazol prophylaxis of hereditary angioedema for dental implant treatment: Case report. Selcuk Dent J, 2019; 6: 190-195
C. Reports Presented in International Scientific Meetings (Proceedings)
C1. Ulu M, Unal ZB, Etoz OA. “Management of a Patient with Papillon-Lefevre Syndrome with Short Dental Implants: A Case Report”, 3rd International Congress of the Oral and Maxillofacial Surgery Society, Antalya, Turkey 2009 (Poster)
C2. Unal ZB, Ulu M, Pala K, Etoz OA. “Immediate Tooth Transplantation Following Cyst Enucleation: A Case Report”, 3rd International Congress of the Oral and Maxillofacial Surgery Society, Antalya, Turkey, 2009 (Poster)
C3. Unal B, Etöz O, Kılıç E, Alkan A. Bishosphonate Related Osteonecrosis of the Jaws: Case Series. 4th AÇBİD International Oral and Maxillofacial Surgery Society Congress. P33.26-30 May 2010, Antalya, Turkey (Oral)
C4. Etöz OA, Demetoğlu D, Gönen ZB, Şekerci AE, Alkan A. An unusual size of mandibular osteoma. 5th AÇBİD International Oral and Maxillofacial Surgery Society Congress and 2nd BAMFS Congress 25-29 May 2011, Antalya, Turkey (Oral)
C5. Çelebi N, Gönen ZB, Kılıç E, Etöz O, Alkan A. “Maxillary sinus floor augmentation in patients with maxillary sinus pseudocyst: case report”. 5th AÇBİD International Oral and Maxillofacial Surgery Society Congress and 2nd BAMFS Congress, sayfa 33, Antalya, Turkey, 25-29 May 2011 (Oral)
C6. Etöz OA, Akçay H, Gönen ZB, Özdamar S, Avunduk MC, Alkan A. Evaluation of the effect of resveratrol on newly formed bone in distraction osteogenesis. 5th AÇBİD International Oral and Maxillofacial Surgery Society Congress and 2nd BAMFS Congress 25-29 Mayıs 2011, Antalya, Turkey (Oral)
C7. Gönen ZB, O. Etöz, A. Alkan. Oral leukoplakia associated to amalgam: healing after replacing amalgam restorations 5th AÇBİD International Oral and Maxillofacial Surgery Society Congress and 2nd BAMFS Congress 25-29 Mayıs 2011, Antalya, Turkey (Poster)
C8. Gönen ZB, Özcan S, Toprak G, Dabanlı D, Şahin FS. Stem cell isolation from human exfoliated deciduous teeth (SHED).1st International Conference/ Workshop on Stem Cell Research and Applications. 7-9 October 2011, Kayseri, TURKEY (Poster)
C9. Toprak G, Özcan S, Gönen ZB, Dabanlı D, Şahin FS. Rabbit Dental Pulp Stem Cell Cultivation. 1st International Conference/ Workshop on Stem Cell Research and Applications. 7-9 October 2011, Kayseri, Turkey (Poster)
C10. Çelebi N, Demirbaş AE, Gönen ZB, Topan C, Alkan A, Kılıç E, Etöz OA. “Is Mandibular Anterior Area a Safe Zone for Implant Placement?’’. 6th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), sayfa 152, Antalya, Turkey, 30 May-3 June 2012 (Poster)
C11. Gönen ZB, Demirbaş AE, Çelebi N, Etöz OA, Alkan A. “Conservative Treatment of Unicystic Ameloblastoma: Report of Two Cases’’. 6th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), sayfa 161, Antalya, Turkey, 30 May-3 June 2012 (Poster)
C12. O.A. Etöz, U. Demetoğlu, Z.B. Gönen, A. Alkan. ‘’Nasal Tooth: Treatment with Transcystic Approach’’, 6th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), Antalya, Turkey, 154, 2012. (Poster)
C13. Etöz, U. Demetoğlu, Z.B. Gönen, E. Soylu, A. Alkan. ‘’Surgical Treatment of Laterally Displaced Post-Traumatic Temporomandibular Joint Ankylosis’’, 6th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), Antalya, Turkey, 77, 2012. (Oral)
C14. O.A. Etöz, Z.B. Gönen, U. Demetoğlu, A. Alkan. ‘’Treatment of Pathological Fracture in A Patient with Bisphosphonate Related Osteonecrosis of the Mandible’’, 6th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), Antalya, Turkey, 114, 2012. (Poster)
C15. Çelebi N, Doğan S, Gönen ZB, Kolçakoğlu KS, Alkan A. “Retrospective analyses of maximum mouth opening in children”. 7th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), sayfa 128, Antalya, Turkey, 29 May-2 June 2013 (Poster)
C16. Kütük N, Baş B, Soylu E, Gönen ZB, Yilmaz C, Balcioğlu E, Özdamar S, Alkan A. “Effect of platelet rich plasma (PRP) on fibrocartilage, hyaline cartilage and bone repair in temporomandibular joint”. 7th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), sayfa 40, Antalya, Turkey, 29 May-2 June 2013 (Oral)
C17. Kütük N, Gönen ZB, Demirbaş AE, Yaşar MT, Alkan A. Retrospective Analysis of Neurosensory Disturbances Related to Dental Implant Placement in the Interforaminal Region. 7th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), sayfa 119, Antalya, Turkey, 29 May-2 June 2013 (Poster)
C18. Demirbaş AE, Çolpak HA, Gönen ZB, Kütük N, Alkan A. “A Retrospective Analysis of Traumatic Bone Cyst of the Jaws”. 7th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), sayfa 119, Antalya, Turkey, 29 May-2 June (Poster)
C19. Gönen ZB, Yılmaz C, Kütük N, Alkan A. Unilateral Facial Nerve Paralysis Caused by Dental Infection. 7th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), sayfa 121, Antalya, Turkey, 29 May-2 June (Poster)
C20. Kütük N, Demirbaş AE, Topan C, Gönen ZB, Alkan A. Neurosensory disturbances related to dental implant placement in the posterior mandible. 7th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD) sayfa 111. Antalya, TÜRKİYE, 29 May-2 June (Poster)
C21. Gönen ZB, E. Kılıç, A. Alkan. Removal of an implant cover cap accidentaly displaced into the mandibular canal. Ağız ve Çene-Yüz Cerrahisi Birliği Derneği 6. Uluslararası Kongresi, 29 May-2 June; Antalya, Turkey (Poster)
C22. Gonen ZB, Ekizer A, Demirci S, Dogan A, Sardogan A, Şahin F, Alkan A. Apical Papilla Stem Cells from Supernumerary Tooth and Comparative Charactarization with Wisdom Tooth. PP-016 AÇBID -BAOMS joint congress in conjuction with 4th Conference of BAMFS, 5-8 November 2014, İstanbul, Turkey (Poster)
C23. Gonen ZB, Bahar D, Salkın H, Ekizer A,Özcan S, Alkan A . Effect of low level laser therapy on viability, apoptosis and senescence of clinical grade adipose derived mesenchymal stem cells. PP-014 AÇBID -BAOMS joint congress in conjuction with 4th Conference of BAMFS, 5-8 November 2014, İstanbul, Turkey (Poster)
C24. Ergen E, Salkın H, Gönen ZB, Özkul Y. “Effect of PRP on human adipose derived mesenchymal stem cells”. 2nd International Congress on Stem Cell and Cellular Therapies, sayfa 162, Antalya, Türkiye, 15-18 Ekim 2015 (Poster)
C25. Özcan S, Acar MB, Alessio N, Galderisi U, Murat A, Mert E, Toprak G, Ömerli F, Öztürk AR, Gönen ZB. “Secretome of naїve senescent mesenchymal stromal cell promotes senesence in ARH-77 myeloma cells: A proteome analysis of changes in secretome composition”. 2nd International Congress on Stem Cell and Cellular Therapies, p 162, Antalya, Türkiye, 15-18 Ekim 2015 (Poster)
C26. Salkın H, Gönen ZB, Bahar D, Taheri S, Özcan S, Kütük N. “TGF-β1 transfection and PRP on chondrogenic differentiation of DP-MSCs”. 2nd International Congress on Stem Cell and Cellular Therapies, sayfa 192, Antalya, Türkiye, 15-18 Ekim 2015 (Poster)
C27. Gönen ZB, Salkın H, Özcan S, Bahar D, Çetin M. “The optimal electroporation parameters for rabbit dental pulp MSCs”. 2nd International Congress on Stem Cell and Cellular Therapies, sayfa 193, Antalya, Türkiye, 15-18 Ekim 2015 (Poster)
C28. Gönen ZB, Bahar D, Taheri S, Salkın H, Ekizer A, Korkmaz K, Çetin M. “Effect of low-level laser therapy on adipose derived hMSCs”. 2nd International Congress on Stem Cell and Cellular Therapies, sayfa 194, Antalya, Türkiye, 15-18 Ekim 2015 (Poster)
C29. Bolat İE, Yazan M, Kaman S, Gonen ZB, Koçyiğit İD, Atıl F, Tekin U, Süer BT, Alkan A. Evaluation of the Effect of Photoionization on Dental İmplant Osseointegration: Experimental Study, ACBID 2015, 9th International Congress, 27-31 Mayıs Antalya-Türkiye. OP-048 (Oral)
C30. Gonen ZB, Dabanli D, Salkin H, Zararsiz G, Dogruel F, Cetin M, “Evaluation of the Effect of Ankaferd on Dental Pulp Derived Mesenchymal Stem Cells and Gingival Fibroblasts”, pp-286 ACBID 2015, 9th International Congress, 27-31 Mayıs Antalya-TÜRKİYE (poster)
C31. Gonen ZB, Dogruel F, Kaynar LG, Asan C, Çetin M. Short-term Danazol Prophylaxis of Hereditary Angioedema for Dental Implant Treatment: Case Report. pp-273 ACBID 2015, 9th International Congress, 27-31 Mayıs Antalya-TÜRKİYE (poster)
C32. Gonen ZB, Asan C, Topan C, Etöz O, Alkan A. Bisphosphonate Related Osteonecrosis of the Mandible Associated with Dental Implants. pp-240 ACBID 2015, 9th International Congress, 27-31 May Antalya-TURKEY (poster)
C33. Dogruel F, Gonen ZB, Canpolat D, Zararsız G, Alkan A. Evaluation of the Correlation between N/L Ratio, MPV and Prognosis of Patient with Severe Dental Infection. pp-268 ACBID 2015, 9th International Congress, 27-31 Mayıs Antalya-TURKEY (poster)
C34. Gonen ZB, Asan C, Şekerci AE, Zararsiz G, Alkan A. Evaluation of Radiologic Changes in Cone Beam CT Images in Bisphosphoante Related Osteonecrosis of the Jaws pp-256 ACBID 2015, 9th International Congress, 27-31 Mayıs Antalya-TÜRKİYE (poster)
C35. Gönen ZB, Soylu E, Dinç G, Bulut N, Kılıç H. Is The Preparation and Application of PRF Safe in Standard Local Operating Room Air? A Prospective Study. 10 th International ACBID Congress, 10-15May 2016, Antalya, Turkey, p 45 (ORAL)
C36. Gönen ZB, Asan C, Bahar D, Salkın H, Balcıoglu E, Ozdamar S. Exosomes Secreted from Dental Pulp Mesenchymal Stem Cells Promote Repair and Regeneration of Temporomandibular Joint in Osteoarthritis. 10 th International ACBID Congress, 10-15May 2016, Antalya, Turkey, p 74 (ORAL)
C37. Mercan U, Gönen ZB, Salkın H, Yalçın Ulker GM, Meral DG. Comparison of the Effect of Postoperative Care Agents on Human Gingival Fibroblasts. 10 th International ACBID Congress, 10-15May 2016, Antalya, Turkey, p 20 (ORAL)
C38. Gönen ZB, Yilmaz Asan C, Dogruel F, Bozkurt S, Bayram F. Evaluation of Temporomandibular Joint Structures in Acromegaly Patients on Cone Beam Computed Tomography Images. 10 th International ACBID Congress, 10-15May 2016, Antalya, Turkey, p 94 (Poster)
C39. Yilmaz Asan C, Gönen ZB, Akkoyun EF, Alkan A. Maxillary Sinus Volumes and Mucosal Thickness of the Patients with Bisphosphonate Related Osteonecrosis of the Jaws. 10 th International ACBID Congress, 10-15May 2016, Antalya, Turkey, p 89 (Poster)
C40. Gonen ZB, Soylu E. Awareness and Knowledge Level of Dentists in Turkey on BRONJ: A Survey Based Study. Turkish Dental Association 23. International Dental Congress, 21-24 September 2017 (oral)
C41. Gonen ZB, Bilge S, Onder ME, Etöz O, Bahar D, Alkan A. Preventive effect of dental pulp-derived mesenchymal stem cells in experimental medication-related osteonecrosis of the jaw”, 23. International Conference on Oral and Maxillofacial Surgery, 31 Mart-3 Nisan 2017, Hong Kong (oral presentation)
C42. Gonen ZB, Alkan A, Uysal T, Ucar F, Kutuk N, Ekizer A, Tasdemir Z. Evaluation of Vestibular Bone Thickness in Class I Malocclusion Treatment with Corticotomy Assisted Rapid Orthodontics. 22-25 August 2014, 11th Asian Congress on Oral and Maxillofacial Surgery, Xian, China (Oral Presentation)
C43. Saraymen B, Karaman I, Gonen ZB, Dogruel F, Koker Y. The Percentages of Endothelial Progenitor Cell with Expression of CD133+, CD 309+, CD34+ at 6. Hour after both Artery Laceration and 20 years tooth Extraction Procedure in Peripheral Blood Samples. 4TH European Congress of Immunology, 6-9 September, Vienna, Austria, 2015 (Poster)
C44. Gonen ZB, Soylu E, Salkın H. The effect of thymoquinone on mesenchymal stem cells from apical papilla. TAOMS (Turkish Association of Oral and Maxillofacial Surgery) 25. International Scientific Congress. 13-17 May 2018, KYRENIA, CYPRUS
C45. Gonen ZB, Dinc G, Bahar D. Assessment of Antimicrobial Effect of Exosomes Secreted from Dental Pulp Mesenchymal Stem Cells. International Association of Oral and Maxillofacial Surgery (IAOMS) in conjunction with 12. ACBID Congress, 9-13 May 2018, Antalya, Turkey
D. Reports Presented in National Scientific Meetings and Published in Proceedings:
D1. Çelebi N, Soylu E, Gönen ZB, Kılıç E, Etöz OA, Alkan A. Retrospective Evaluation of Dental Implant Success: Three to Five Years Follow Up. 5. ITI Turkish Congress, İstanbul, Turkey, 21-22 Mayıs 2011, (Oral)
D2. Ekizer A, Bozkurt S, Gönen ZB, Ekizer E. Evaluation of the Airway in different malocclusion types. 13.Turkish Orthodontics Congress .3-5 November 2013, İstanbul, Turkey (Poster)
D3. Ekizer A, Gönen ZB, Altınpulluk MÖ, Uysal T, Alkan A. The effect of corticotomy on treatment time in Class I Malocllusion 13. Turkish Orthodontics Congress. 3-5 November 2013, İstanbul, Turkey (Poster)
D4. Doğruel F, Gönen ZB, Canpolat DG, Ocak H, Bayram F. Evaluation the level of Vitamin D in Dental Faculty. 37. Turkish Endocrinology and Metabolism Disorders Congress, page 387, Antalya, Turkey, 6-10 May 2015 (Poster)
D5. Canpolat DG, Gönen ZB, Doğruel F, Şengül İ, Yıldız K, “Determination of Cardiopulmonary Resuscitation Knowledge Level of Dentists.” Turkish Association of Anesthesiology and Reanimation 49. National Congress, s1, Antalya, Turkey, 2-6 Aralık 2015 (oral p)
D6. Gönen ZB, Canpolat DG, Yay A, Bahar D, Kütük N, Çolpak H, Yalçın B, Alkan A. “Effect of dental pulp derived mesenchymal stem cells on mental nerve repair”. Turkish Association of Anesthesiology and Reanimation 49. National Congress, p 39, Antalya, Turkey, 2-6 December 2015 (Poster)
D7. Canpolat DG, Doğruel F, Gönen ZB, Yılmaz C, Zararsız G, Alkan A. “The role of PLT, MPV, MPV/PLT ratio in prediction of PONV in children after deep sedation”. Turkish Association of Anesthesiology and Reanimation 49. National Congress, p 761, Antalya, Turkey, 2-6 December 2015 (Poster)
D8. Canpolat DG, Gönen ZB, Durdu T. “Evaluation of Approaches of the Dentists to General Anesthesia in the Clinical Practice.” Turkish Association of Anesthesiology and Reanimation 49. National Congress, p 851, Antalya, Turkey, 2-6 December 2015 (Poster)
D9. Bayram F, Gönen ZB, Doğruel F, Öztürk S, Şenol S, Kurtsoy A. Investigation of the changes in craniomandibular bony changes in new diagnosed acromegaly patients: cone beam CT study. 38. Turkish Endocrinology and Metabolic Diseases Congress, sayfa 357, Antalya, Turkey, 11-15 Mayıs 2016 & 2. National Lipid Symposium 14 May 2016 (Poster)
D10. Geçor O, Polat S, Acar AH, Gonen ZB, Keleş A, Ataç MS. Investigaton of different biomaterials on perimplant defect healing. 22nd Turkish Association of Oral and Maxillofacial Surgery, TAOMS 2015 19–23 May 2015.OP-05 Bodrum, Muğla, Turkey (oral p)
D11. Soylu E, Gönen ZB, Alkan A. ‘’A New Detection Method for Submerged Implants: Oral Tattoo", 22nd Turkish Association of Oral and Maxillofacial Surgery, TAOMS 2015 19–23 May 2015.PP 161 Bodrum, Muğla, Turkey (Poster)
COURSES ATTENDED
Memberships in Scientific Organizations
SUPERVISED THESIS
Doctorate
Süheyb BİLGE, Radiological and Biochemical Evaluation of the Efficiency of Stem Cell Applications in Experimental Bisphosphonate Osteonecrosis of the Jaw, Erciyes University / Institute of Health Sciences / Department of Oral and Maxillofacial Surgery, 2016 Completed (Supervisor)
Dilek BAHAR, Investigation of the Effect of Umbilical Cord derived Mesenchymal Stem Cell Exosomes -Chitosan / Hydroxyapatite Biomaterials on the Bone Regeneration, Institute of Sciences, Biology Department, 2019 (Assistant Supervisor)
Master of Science
Buket Banu ÖZKAN, Investigation of Clinically Applicable Production Conditions of Platelet Rich Fibrin-Derived Mesenchymal Stem Cells. Health Sciences Institute, Department of Stem Cell Sciences, 2019 (Supervisor)
Nur Seda ŞAHİN, Evaluation of the Effect of Hypoxic Medium on Microvesicle Activity. Health Sciences Institute, Department of Stem Cell Sciences. 2019 (Supervisor)
Ravza Tosunbayraktar, Investigation of Adipose Tissue Matrix Decellularization Methods, Health Sciences Institute, Department of Stem Cell Sciences. 2020 (Supervisor)
Genome and Stem Cell Center (GENKOK)
Dr. Zeynep Burçin GONEN received her DDs degree and graduated with an honour degree from Faculty of Dentistry, Ondokuz Mayıs University (Turkey). She trained in the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Erciyes University, Kayseri, Turkey; and received her specialization and PhD degree in Oral and Maxillofacial Surgery (OMFS). She had Immunology MSC degree from the same university.
Dr. Gonen trained for facial plastic surgery at Facial Plastic Surgery and OMFS department at Poole Hospital NHS, UK,. She had Associate Professor Degree in Oral and Maxillofacial Surgery in 2019. Dr. Gonen is Director of mesenchymal stem cell production unit of Erciyes University, Genome and Stem Cell Center (GENKÖK) since 2014. She is a member of Cell Therapy and Immunology Group at the Turkish Health Institutes of Turkey.
Dr. Gonen is one of the representatives of NEXTGEN-Europe in International Association of Oral and Maxillofacial Surgeons (IAOMS).
EDUCATION
2007-2013 Residency Specialty Training including PhD, Department of Oral and Maxillofacial Surgery, Erciyes University, Kayseri, Turkey. PhD Thesis: Evaluation of Vestibular Bone Thickness in Class I Malocclusion Treatment with Corticotomy Assisted Rapid Orthodontics Supervisor: Prof. Alper ALKAN
2002-2007 Faculty of Dentistry Ondokuz Mayıs University, Samsun, Turkey
1995-2002 Anadolu College, Amasya, Turkey (5.0/ 5.0)
QUALIFICATIONS
Associate Professorship: 2019 Oral and Maxillofacial Surgery, Interuniversity Board of Turkey
Specialist: 2014 Oral and Maxillofacial Surgery, Turkish Health of Ministry
PhD: 2013 Department of Oral and Maxillofacial Surgery, Institute of Health, Erciyes University, Kayseri, Turkey
DDS: 2007 Faculty of Dentistry, Ondokuz Mayıs University, Samsun, Turkey
Rotations in Training
2009 Department of Anesthesiology and Reanimation, Faculty of Medicine, Erciyes University, Kayseri, Turkey (2 months)
2010 Department of Otorhinolaryngology, Faculty of Medicine, Erciyes University, Kayseri, Turkey (3 months)
2011 Department of Emergency, Faculty of Medicine, Erciyes University, Kayseri, Turkey (2 months)
International Experience
2006-2007 Vilnius University, Medical Faculty, Institute of Odontology, Vilnius, Lithuania (6 months)
2017 Honorary Observership/ Fellowship in Facial Plastic Surgery, Oral and Maxillofacial Surgery, 5 Jun -7 Aug, Poole Hospital NHS, United Kingdom (Prof V. Ilankovan, 2 months)
2020 Fellowship in Facial Plastic Surgery, Oral and Maxillofacial Surgery, 20 February 2020 – 19 August 2020, Poole Hospital NHS, United Kingdom (Prof V. Ilankovan, 6 months)
CURRENT POSITIONS
2014-ongoing Assistant Professor (PhD Teaching Staff), Erciyes University, Kayseri, TR
2014- ongoing Vice Director, Genome and Stem Cell Center, Erciyes University
2015- ongoing Production Manager of GMP laboratory, Stem Cell Unit, Erciyes University
Committee Positions
2014-ongoing Occupational Health and Safety Committee, Member, Erciyes University
2017-ongoing Infection Control Committee, President, Genome and Stem Cell Center
2017-ongoing Turkish National Institutes of Health (TÜSEB), Cancer Institute, Immunology and Cellular Therapy Group, Member, Ankara, Turkey
2018-ongoing Quality Control Committee, Member, Erciyes University, Kayseri, Turkey
2018-ongoing Social and Cultural Events Committee, President, Genome and Stem Cell Center
2018-ongoing Turkish Academy of Sciences (TÜBA), Working Group of Stem Cell, Member, Ankara, Turkey
EMPLOYMENT HISTORY
2007-2013 Resident, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Erciyes University, Kayseri, Turkey
2010- ongoing Private Practice, Kayseri, TR (part time)
2014-2016 Oral and Maxillofacial Surgeon, Hospitadent International Dental Hospital, Kayseri, TR (part time)
AWARDS
Honors Graduate 2007 Ondokuz Mayıs University, Samsun, Turkey
Valedictorian 2007 Faculty of Dentistry, Ondokuz Mayıs University, Samsun, TR
PRIZES
2014 Oral Presentation of Young Doctors award, 11th Asian Congress on Oral and Maxillofacial Surgery, ‘’Evaluation of Vestibular Bone Thickness in Class I Malocclusion Treatment with Corticotomy Assisted Rapid Orthodontics ‘’, XIAN, China
2014 Oral presentation award, International Congress of Oral and Maxillofacial Surgery Society (ACBID) ‘’Stem Cell Application in Alveolar Cleft: An Experimental Study’’, Antalya, Turkey
2014 Best Poster Award, BAOMS-ACBID Joint Congress (British Association Oral and Maxillofacial Surgeons and Oral and Maxillofacial Surgery Society), ‘’ Apical Papilla Stem Cells from Supernumerary Tooth and Comparative Characterization with Wisdom Tooth ‘’ İstanbul, Turkey
2015 Best Poster award, International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), “Evaluation of the Effect of Ankaferd on Dental Pulp Derived Mesenchymal Stem Cells and Gingival Fibroblasts” Antalya, Turkey
2015 Oral Presentation Award (Third Place), International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), ‘’Evaluation of the Effect of Photoionization on Dental Implant Osseointegration: Experimental Study’’ Antalya, Turkey
2016 Best Oral Presentation Award, International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), ‘’ Exosomes Secreted from Dental Pulp Mesenchymal Stem Cells Promote Repair and Regeneration of Temporomandibular Joint in Osteoarthritis’’. Antalya, Turkey
2017 Dogsan Science Award, Turkish Society of Plastic-Reconstructive and Esthetics Surgeons (Second Place in Research Category), ‘’ Effect of Mesenchymal Stem Cells in Sciatic Nerve Repair: Functional, Electrophysiological and Histomorphometric and Immunohistochemically Analysis’ ’Antalya, Turkey
2018 Innovative Dentist of the Year’ DoktorClub Award, Turkey
2021 Science Award, Turkish Society of Plastic-Reconstructive and Esthetics Surgeons (First Place in Research Category), ‘’ 3D Chitosan-Heparin Tissue Scaffold with Mesenchymal Stem Cells for chondrogenesis: in vitro and in vivo study’ ’Antalya, Turkey
COURSES GIVEN
- Stem Cells in Regenerative and Reconstructive Surgery (Theorical/ Practical)
- Oral and Maxillofacial Diseases and Treatments (Practical)
- Mesenchymal stem cell production Hands on Courses
- Dental Handpieces, Equipments and Sterilization Methods (Theorical/ Practical)
- Ethics in Dentistry (Theorical)
RESEARCH GRANTS OBTAINED
Competitive research grants from public funding authorities
- Etoz O, Alkan A, Gonen ZB. 'Investigation of the Effect of Resveratrol on New Bone Formation in Distraction Osteogenesis'. Scholarship, Supported by TUBITAK (The Scientific Research Council of Turkey), Project No. 109S200, Project Budget: 10.000 TL (~ 2.500 USD), 01. Sep.2009-01. Sep.2010
- Gonen ZB, Ozcan S, Galderisi U. 'Assessment of the Biological Effects of Senescent Mesenchymal Stem Cell Secretomes on Cancer Cell Lines'. Principle Investigator, Supported by TUBITAK (The Scientific Research Council of Turkey), Project No. 114S873, Project Budget: 29.900 TL (~ 7.475 USD), 15. Dec.2014-15. Dec.2015
- Alkan A, Gonen ZB, Karakükcü M, Sahin F. ‘Repair of Alveolar Clefts Through Stem Cell Application Using a Customizable Scaffold’. Co-Principal Investigator, Supported by TUBITAK (The Scientific Research Council of Turkey), Project No. 213S184, Project Budget: 457.705 TL (~ 114.425 USD), 01. Oct.2014 - 01. Oct.2016
- Kutuk N, Gonen ZB, Ozcan S, Ozdamar S. 'Investigation of the Effects of Stem Cell and Plateletten Rich Plasma (PRP) on Fibrocartilage and Bone Repair in Experimental Temporomandibuler Joint Osteoarthritis'. Co-Principal Investigator, Supported by TUBITAK (The Scientific Research Council of Turkey), Project No. 114S370, Project Budget: 226.513 TL (~ 56.626 USD), 15. Oct.2014-15. Oct.2016
- Gonen ZB, Etoz O, Bilge S, Alkan A. 'Evaluation of the Efficiency of Mesenchymal Stem Cells on Bisphosphonate Related Osteonecrosis of the Jaw'. Principle Investigator, Supported by TUBITAK (The Scientific Research Council of Turkey), Project No. 113S991, Project Budget: 178.500 TL (~ 44.620 USD), 15. April. 2014-15. Oct.2017
- Sezer G, Ozkul Y, Gonen ZB, Yılmaz S. 'The Effect of Bone Marrow Derived Stem Cells on Paclitaxel and Cisplatin Generated Neuropathic Pain.' Researcher, Supported by TUBITAK (The Scientific Research Council of Turkey), Project No. 315S176, Project Budget: 29.900 TL (~ 7.475 USD), 15. Jul.2016-15. Oct.2017
- Alp Mese E, Gonen ZB, Cetin M, Coruhlu A, Gundogan K, Doganay M, Cetin A, Karakukcu M, Kaynar L. 'Investigation of the Effect of Mesenchymal Stem Cell Therapy on Survival in Severe Sepsis and Septic Shock Patients', Researcher, Supported by TUBITAK (The Scientific Research Council of Turkey), Project No. 117S053, Project Budget: 545.325 TL (~ 136.338 USD), 01. Dec.2017-ongoing (Dec 2019)
- Ozkul Y, Cetin M, Gonen ZB, Ibis EK, Pinarbasi MB. ‘Erciyes Cord Blood and Tissue Bank’ Researcher, Supported by Central Anatolia Development Agency (ORAN), Project Budget: 1.249.142,69 TL (~ 312.285 USD), 17. Aug.2017- ongoing (Aug.2019)
Competitive research grants from the Scientific Research Support Division of University
- Alkan BA, Gonen ZB, Alkan A, Ekizer A, Ozcan S, Ozkul Y, Taheri S, Sonmez MF, Arslan K, Toprak G. ‘Stem Cell Applications in Alveolar Cleft Repair: An Experimental Study’. Researcher, Supported by Erciyes University Project Budget: 39.846,73 TL (~ 9.960 USD), 16. May.2012-12. Feb.2014
- Kutuk N, Alkan A, Soylu E, Gonen ZB, Ozdamar S, Yay AA, Alkan BA. ‘The effects of stainless steel and titanium curette on bone healing in experimentally prepared peri-implantitis treatment. ‘Researcher, Supported by Erciyes University, Project Budget: 403.146,25TL (~ 100.785 USD), 26. Apr.2012-17. Jun.2014
- Mutlu M, Gonen ZB, Ozkul Y, Gunay M. ‘Effect of local stem cell application on healing in diabetic foot: Clinical Trial’. Researcher, Supported by Erciyes University Project Budget: 99.900,00 TL (~ 24.970 USD), 18. Mar.2015-18. Sep.2016
- Oner A, Sahiner M, Karaca C, Bahar D, Ozkul Y, Gonen ZB. ‘Effect of Anti-VEGF on Retina Pigment Epithelial Cells’. Researcher, Supported by Erciyes University Project Budget: 29.317,36 TL (~ 7.320 USD), 24. Jul.2015-05. Oct.2016
- Halici M, Cerrah M, Baskol G, Ozturk A, Dogan S, Ozkul Y, Olcar HA, Lekesizcan A, Ozdamar S, Gonen ZB. ‘The effects of locally administered Mesenchymal Stem cell treatment in the experimental diabetic rat femur non-union model’. Researcher, Supported by Erciyes University Project Budget: 32.814,82 TL (~ 8.200 USD), 23. Feb.2015-30. Dec.2016
- Kutuk N, Gonen ZB, Ozdamar S, Colpak HA. ‘Simultaneous Dental Implant Placement and Vertical Alveolar Augmentation with Bone Graft and Dental Pulp Stem Cells: Histological and Histomorphometric Study in Sheep Model’. Researcher, Supported by Erciyes University Project Budget: 30.623,86 TL (~ 7.650 USD), 24. Mar.2016-31. Jul.2017
- Ozkul Y, Ergen E, Gonen ZB. ‘Osteogenic Differentiation of Mesenchymal Stem Cells by Conditional Medium: An Experimental Study.’ Researcher, Supported by Erciyes University Project Budget: 14.984,02 TL (~ 3.745 USD), 22. May.2015-07. Nov.2017
- Oner A, Gonen ZB, Cetin M. ‘Stem Cell Application in Retinitis Pigmentosa: Clinical Trial’. Researcher, Supported by Erciyes University Project Budget: 31.600,00 TL (~ 7.900 USD), 02. Dec 2015-23. Jun.2017
- Ozkul Y, Ozcan S, Gonen ZB, Zararsiz G, Ozturk AR. ‘Detection of Hereditary Single Gene Diseases by New Generation Sequencing Technique in Central Anatolia Region’. Researcher, Supported by Erciyes University Project Budget: 1.296.000,00 TL (~ 324.100 USD), 05. Aug.2014-06. Apr.2017
- Cetin M, Pinarbasi MB, Gonen ZB, Polat S. ‘Temperature Monitoring System and Connected Security Monitoring System of the Research Center’. Researcher, Supported by Erciyes University, Project Budget: 362.260,00 TL (~ 90.565 USD), 03. Aug.2015-03. Jan.2018
- Unal A, Ozkul Y, Kaynar L, Bugday G, Gonen ZB, Celikzincir H, Avcilar H. ‘Dendritic Cell Production from Autologous Stem Cells and Mononuclears Cells Against Multiple Myeloma Cells (Tumor Vaccine).’ Researcher, Supported by Erciyes University, Project Budget: 15.494,42 TL (~ 3.975 USD), 21. Jul.2016-12. Apr.2018
- Gonen ZB, Sahin NS. ‘Evaluation of the Effect of the Hypoxic Media on Micro Vesicles’ Principle Investigator. Supported by Erciyes University, Project No:7712, Project Budget: 14.999,32 TL (~ 3.745 USD), 23. 08 December 2017- ongoing (Dec.2018)
- Gonen ZB, Cetin M, Salkin H, Sav H, Kaynar L, Dogruel F, Ozcan I. 'The Effect of Neutrophil-Derived Exosomes on Fungal Biofilm'. Co-Principle Investigator, Supported by Erciyes University, Project Budget: 48.954,62 TL (~ 12.200 USD), 04. Apr.2017-ongoing (Oct.2018)
- Karaman I, Gonen ZB, Dogan S, Aycan BM, Karaman ZF, Gunay AE, Güney A, Demirpolat E. ‘Investigation of The Effectiveness of Wharton Jelly Derived Stem Cells in the Treatment of Severe Osteoarthritis: Clinical Trial’. Researcher, Supported by Erciyes University, Project Budget: 77.577,90 TL (~ 19.390 USD), 18. Dec.2017-ongoing (Dec.2019)
- Ünlü M, Gonen ZB. ‘Stem cell application in degenerative retina and optic nerve diseases: Clinical Trial’ Researcher. Supported by Erciyes University, Project No: 7816, Project Budget: 49.464 TL (~ 12.365 USD), 23 February 2018- ongoing (Feb.2019)
INVITED LECTURES
- “Cell Therapies in Dentistry”. International 2nd Seminar on Embryonic Stem Cell, Training course 1-3 on Management and Business of Stem Cell Technologies and Basic of Mammalian Cell Culture, GENEOCELL Company and Erciyes University, 1-3 December 2010, Kayseri, Turkey
- Teaching Staff at the Intensive Program “Stem Cell Applications: From Bench Side to Bed Side” (10 days’ intensive course) 26 May- 6 June 2014, Gyor, Hungary
- “Mesenchymal Stem Cell Applications in Regenerative Therapy: Bench to Bedside”. 2nd International Congress on Stem Cell and Cellular Therapies, 15-18 October 2015 Antalya, Turkey “Mesenchymal Stem Cell and Clinical Translation”, 3. Hands On Cell Culture Course, 9-13 March 2015, Kayseri, Turkey
- “Cellular Therapy in Dentistry”, Hands on Oral Fibroblast and Mesenchymal Stem Cell Culture Course, 4-6 May 2015, Kayseri, Turkey
- “Donor Criteria in Cell Therapies” Turkish Academy of Science, 3. International Stem Cell Course in Lymphoma-Myeloma Congress, 19-22 May 2016, Antalya, Turkey
- “Mesenchymal Stem Cell and Clinical Translation’’, 4. Hands On Cell Culture Course, 11-13 February 2016, Kayseri, Turkey
- “Cellular Therapy Products for Clinics”, Cell Therapy Symposium, Acıbadem University, 19 March 2016, İstanbul, Turkey
- “GMP-grade Mesenchymal Stem Cells” Turkish Association of Nuclear Medicine, Preclinical Imaging Group Organization 21-23 January 2017, Kayseri, Turkey
- “Stem Cell Usage and Current GENKÖK Projects” International Advanced Cellular and Molecular Workshop, Feb 12-16 2018, Kayseri, Turkey
- “What is Mesenchymal Stem Cell and How to Produce?” XI. National Blood Banks and Transfusion Congress, 11 – 15 March 2018, Antalya Turkey
- “Mesenchymal Stem Cell Applications in OMFS: From Bench to Bedside” International Association of Oral and Maxillofacial Surgery (IAOMS) in conjunction with 12. ACBID Congress, 9-13 May 2018, Antalya, Turkey
- “Stem Cell Applications in OMFS” 24th International Conference on Oral and Maxillofacial Surgery (ICOMS), 21-24 May 2019, Rio de Jenerio, Brazil
PUBLICATIONS
A. Articles Published in International Refereed Journals *Surname was changed to ‘Gonen’ in 2010.
A1. Turgut M, Kaplan S, Unal BZ, Bozkurt M, Yürüker S, Yenisey C, Sahin B, Uyanıkgil Y, Baka M. Stereological analysis of sciatic nerve in chickens following neonatal pinealectomy: an experimental study. J Brachial Plex Peripher Nerve Inj. 2010 Apr 21;5:10.
A2. Çelebi N, Gönen ZB, Kılıç E, Etöz OA, Alkan A. Maxillary Sinus Floor Augmentation in Patients with Maxillary Sinus Pseudocyst: Case Report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Dec;112(6): 97-102.
A3. Kılıç E, Gönen ZB, Alkan A. Osteonecrosis related to oral bisphosphonate usage: case report and review of treatment strategies. J Int Dent Med Res 5(1): 45-48 (2012)
A4. Kütük N, Demirbaş AE, Gönen ZB, Topan C, Kiliç E, Etöz OA, Alkan A. Anterior mandibular zone safe for implants. J Craniofac Surg. 2013 Jul;24(4): 405-8
A5. Kütük N, Baş B, Soylu E, Gönen ZB, Yilmaz C, Balcioğlu E, Özdamar S, Alkan A. Effect of platelet rich plasma (PRP) on fibrocartilage, hyaline cartilage and bone repair in temporomandibular joint. J Oral Maxillofac Surg. 2014 Feb;72(2):277-84
A6. Kütük N, Gönen ZB, Yaşar MT, Demirbaş AE, Alkan A. Reliability of panoramic radiography in determination of neurosensory disturbances related to dental implant placement in posterior mandible. Implant Dent. 2014 Dec;23(6):648-52.
A7. Ozcan S, Alessio N, Acar B, Toprak G, Gonen ZB, Peluso G, Galderisi U. Myeloma cells can corrupt senescent mesenchymal stromal cells and impair their anti-tumor activity. Oncotarget. 2015 Nov 24;6(37):39482-92.
A8. Oner A, Gonen ZB, Sinim N, Cetin M, Ozkul Y. Subretinal adipose tissue-derived mesenchymal stem cell implantation in advanced stage retinitis pigmentosa: a phase I clinical safety study. Stem Cell Res Ther. 2016 1;7(1):178.
A9. Abbas OL, Borman H, Uysal ÇA, Gönen ZB, Aydin L, Helvacioğlu F, Ilhan Ş, Yazici AC. Adipose-Derived Stem Cells Enhance Axonal Regeneration through Cross-Facial Nerve Grafting in a Rat Model of Facial Paralysis. Plast Reconstr Surg. 2016 Aug;138(2):387-96.
A10. Gönen ZB, Yılmaz Asan C, Etöz O, Alkan A. Oral leukoplakia associated with amalgam restorations. J Oral Sci. 2016;58(3):445-8.
A11. Ozcan G, Sekerci AE, Gönen ZB. Are there any differences in mandibular morphology of patients with bisphosphonate-related osteonecrosis of jaws?: a case-control study. Dentomaxillofac Radiol. 2016 Jun 1:20160047l.
A12. Canpolat DG, Dogruel F, Gönen ZB, Yılmaz C, Zararsız G, Alkan A. The role of platelet count, mean platelet volume, and the mean platelet volume/platelet count ratio in predicting postoperative vomiting in children after deep sedation. Saudi Med J. 2016 Oct;37(10):1082-8.
A13. Kaynar L, Demir K, Turak EE, Öztürk ÇP, Zararsız G, Gönen ZB, Gökahmetoğlu S, Şıvgın S, Eser B, Köker Y, Solmaz M, Ünal A, Çetin M. TcRαβ-depleted haploidentical transplantation results in adult acute leukemia patients. Hematology. 2017;22(3):136-144.
A14. Gönen ZB, Yılmaz Asan C. Treatment of bisphosphonate-related osteonecrosis of the jaw using platelet-rich fibrin. Cranio. 2017 Sep;35(5):332-336.
A15. Sayan A, Gonen ZB, Ilankovan V. Multiple metastases to bone from squamous cell carcinoma of the oropharynx: unusual findings on positron emission tomography-computed tomography. Br J Oral Maxillofac Surg. 2017 ;55(10):1044-1045.
A16. Cetin M, Akyol G, Gonen ZB, Keklik M, Zararsiz G, Unal A, Tiren-Verbeet NL, Kaynar L. Additional infusions of mesenchymal stem cells improve response rate in multidrug-resistant GvHD patients. Bone Marrow Transplant. 2017 ;52(5):783-785.
A17. Keni N, Kaynar L, Ünal A, Demir K, Ermis Turak E, Gönen ZB, Şıvgın S, Eser B, Ünal A, Çetin M. Transplantation of Single Mismatch Hematopoietic Stem Cells with Third Party Mesenchymal Stem Cells for Severe Aplastic Anemia: A Case Report and Mini Review. Ann Hematol Oncol. 2017; 4(5): 1150.
A18. Dogruel F, Gonen ZB, Gunay-Canpolat D, Zararsiz G, Alkan A. The Neutrophil-to-Lymphocyte ratio as a marker of recovery status in patients with severe dental infection. Med Oral Patol Oral Cir Bucal. 2017 Jul 1;22(4): 440-445.
A19. Soylu E, Gönen ZB, Alkan A. A New Detection Method for Submerged Implants: Oral Tattoo. J Prosthodont. 2018 Apr;27(4):361-363.
A20. Gönen ZB, Yillmaz Asan C, Zararsiz G, Kiliç E, Alkan A. Osseous changes in patients with medication - related osteonecrosis of the jaws. Dentomaxillofac Radiol 2018; 47(1):20170172.
A21. Abbas OL, Özatik O, Gönen ZB, Öğüt S, Özatik FY, Salkın H, Musmul A. Comparative Analysis of Mesenchymal Stem Cells from Bone Marrow, Adipose Tissue, and Dental Pulp as Sources of Cell Therapy for Zone of Stasis Burns. J Invest Surg 2019;32(6):477-490.
A22. Şahiner M, Bahar D, Öner A, Gönen ZB, Ünlü M, Gülmez Sevim D, Karaca Ç, Mirza GE. The Effects of Anti-Vascular Endothelial Growth Factor Drugs on Retinal Pigment Epithelial Cell Culture. Turk J Ophthalmol. 2018 Aug;48(4):190-195.
A23. Abbas OL, Özatik O, Gönen ZB, Öğüt S, Entok E, Özatik FY, Bahar D, Bakir ZB, Musmul A. Prevention of Burn Wound Progression by Mesenchymal Stem Cell Transplantation: Deeper Insights Into Underlying Mechanisms. Ann Plast Surg. 2018 Dec;81(6):715-724.
A24. Çolpak HA, Gönen ZB, Özdamar S, Alkan A, Kütük N. Vertical ridge augmentation using guided bone regeneration procedure and dental pulp derived mesenchymal stem cells with simultaneous dental implant placement: A histologic study in a sheep model. J Stomatol Oral Maxillofac Surg. 2019;120(3):216-223.
A25. Yazan M, Kocyigit ID, Atil F, Tekin U, Gonen ZB, Onder ME. Effect of hyaluronic acid on the osseointegration of dental implants. Br J Oral Maxillofac Surg. 2019;57(1):53-57.
A26. Dogruel F, Gonen ZB, Canpolat DG, Ocak H, Bayram F. Investigation of Vitamin D levels in medical staff in a dental clinic. Niger J Clin Pract. 2019;22(4):573-577.
A27. Abbas OL, Özatik O, Gönen ZB, Koçman AE, Dağ I, Özatik FY, Bahar D, Musmul A. Bone Marrow Mesenchymal Stem Cell Transplantation Enhances Nerve Regeneration in a Rat Model of Hindlimb Replantation. Plast Reconstr Surg. 2019;143(4):758-768.
A28. Oner A, Gonen ZB, Sevim DG, Smim Kahraman N, Unlu M. Suprachoroidal Adipose Tissue-Derived Mesenchymal Stem Cell Implantation in Patients with Dry-Type Age-Related Macular Degeneration and Stargardt's Macular Dystrophy: 6-Month Follow-Up Results of a Phase 2 Study. Cellular Reprogramming Vol. 20, No. 6 Dec 2018.ahead of print http://doi.org/10.1089/cell.2018.0045.
A29. Salkın H, Gönen ZB, Ergen E, Bahar D, Çetin M. Effects of TGF-β1 Overexpression on Biological Characteristics of Human Dental Pulp-derived Mesenchymal Stromal Cells. Int J Stem Cells 2019;12(1):170-182.
A30. Gonen ZB, Colpak HA, Onger ME. Effects of Bisphosphonate Treatment on Mandibular Condyle Tissues of Temporomandibular Joint: A Stereological Study. J Stomatol Oral Maxillofac Surg. 2019;120(6):513-516.
A31. Mercan U, Gonen ZB, Salkin H, Yalcin Ulker GM, Meral DG. Comparison of the effect of postoperative care agents on human gingival fibroblasts: a preliminary study. Eur Oral Res. 2019;53(2):67-73.
A32. Oner A, Gonen ZB, Sevim DG, Sinim Kahraman N, Unlu M. Six-month results of suprachoroidal adipose tissue-derived mesenchymal stem cell implantation in patients with optic atrophy: a phase 1/2 study. Int Ophthalmol. 2019;39(12):2913-2922.
A33. Gonen ZB, Alkan A, Ekizer A, Kutuk N, Tasdemir Z. Evaluation of Vestibular Bone Thickness in Class I Malocclusion Treatment With Corticotomy-Assisted Rapid Orthodontics. J Craniofac Surg. 2019;30(8):727-733.
A34. Salkın H, Gönen ZB, Özcan S, Bahar D, Lekesizcan A, Taheri S, Kütük N, Alkan A. Effects of combination TGF-B1 transfection and platelet rich plasma (PRP) on three-dimension chondrogenic differentiation of rabbit dental pulp-derived mesenchymal stem cells. Connect Tissue Res. 2021 Mar;62(2):226-237.
A35. Olçar HA, Halıcı M, Kafadar İH, Karaman İ, Lekesizcan A, Gönen ZB. Can injection of adipose stem cells to non-union zone increase bone union? Experimental rat study. Jt Dis Relat Surg. 2020;31(1):20-27.
A36. Sayan A, Coftas R, Gonen ZB, Ilankovan V. Head and neck/maxillofacial nurse-led clinical activity during COVID-19 Pandemic - experience of one unit [published online ahead of print, 2020 Aug 3]. Br J Oral Maxillofac Surg. 2020;S0266-4356(20)30376-4.
A37. Uzun E, Güney A, Gönen ZB, Özkul Y, Kafadar İH, Günay M, Mutlu M. Intralesional allogeneic adipose-derived stem cells application in chronic diabetic foot ulcer: Phase I/2 safety study [published online ahead of print, 2020 Aug 13]. Foot Ankle Surg. 2020;S1268-7731(20)30169-7.
A38. Goh M, Gönen ZB, Sayan A, Ilankovan V. Evolution of surgical modalities in the management of rhinophyma: our experience. Br J Oral Maxillofac Surg. 2021 Feb;59(2):222-227.
A39. Sayan A, Gonen ZB, Ilankovan V. Adverse reactions associated with perioral rejuvenation using laser, fat and hyaluronic acid: systematic review. Br J Oral Maxillofac Surg. 2021 Nov;59(9):1005-1012.
A40. Kemaloğlu CA, Özyazgan İ, Gönen ZB. Immediate fat and nanofat-enriched fat grafting in breast reduction for scar management. J Plast Surg Hand Surg. 2021 Jun;55(3):173-180.
B. Articles Published in National Refereed Journals
B1. Turgut M, Kaplan S, Ünal ZB, Altunkaynak Z, Ünal D, Şahin B, Bozkurt M, Yurtseven ME. Effects of Pinealectomy on Morphological Features of Blood Vessel in Chicken: An Electron Mıcroscopıc and Stereologıcal Study. J Experiment and Clin Med 2009; 29(3):112-118.
B2. Çelebi N, Soylu E, Gönen ZB, Etöz O, Kiliç E, Alkan A. Retrospective Evaluation of Dental Implant Success: Three to Five Years Follow Up. Cumhuriyet Dent J. 16(1), 20-24 (2013)
B3. Çelebi N, Gönen ZB, Alkan A. Massive Odontogenic Cyst Deviating Nasal and Maxillary Sinus Floor. Journal of Health Sciences, 22(1), 99-101 (2013)
B4. Etöz O, Gönen ZB, Deniz K, Alkan A. Pleomorphic Adenoma in Upper Lip Mucosa: A Clinical Report. Cumhuriyet Dent J 16 (3): 213-216, 2013.
B5. Etöz OA, Gönen ZB, Akçay H, Günhan Ö, Alkan A. Odontogenic Myxoma of the Maxilla with Soft Tissue Involvement: Case Report. Turkish Clinics J Dental Sci 2014;20(3):191-4.
B6. Demetoglu U, Gönen ZB, Asan C, Kılıç E, Alkan A. An Impacted Ectopic Wisdom Tooth that Caused Pulpitis Pain on the Second Molar: A Case Report. Journal of Health Sciences 2015; 24: 120-123.
B7. Gönen ZB, Asan C, Kütük N, Alkan A. Unilateral Facial Nerve Paralysis Caused by Dental Infection. J Dent Fac Atatürk Uni. Supplement: 14, 2016: 32-36
B8. Gönen ZB, Soylu E, Akbulut N. Stem Cell Applications in Oral and Maxillofacial Surgery. Turkish Clinics J Oral Maxillofac Surg-Special Topics 2016;2(2) :36-41
B9. Soylu E, Gönen ZB, Akbulut N. Biomedical Approach to Tissue Engineering in Maxillofacial Surgery and Applications. Turkish Clinics J Oral Maxillofac Surg-Special Topics 2016;2(2) :48-52.
B10. Ekizer A, Gonen ZB, Topsakal KG. Biomechanics and Disorders of Temporomandibular Joint. Turkish Clinics J Orthod-Special Topics 2016;2(2):9-17.
B11. Gonen ZB. The Evaluation of Electroporation Parameters for Dental Pulp Mesenchymal Stem Cells. Journal of Health Sciences. 2016; 25: 144-147.
B12. Canpolat D, Gönen ZB, Durdu T. Evaluation of Approaches of the Dentists to General Anesthesia in the Clinical Practice. J Dent Fac Atatürk Uni. 2016, 26 (3): 389-393.
B13. Canpolat D, Gönen ZB, Dogruel F, Şengül İ, Yıldız K. Determination of Cardiopulmonary Resuscitation Knowledge Level of Dentists. Gaziantep Medical Journal 2016;22(4):197-201
B14. Gönen ZB, Doğruel F, Yılmaz Asan C, Kaynar L, Çetin M Short-term danazol prophylaxis of hereditary angioedema for dental implant treatment: Case report. Selcuk Dent J, 2019; 6: 190-195
C. Reports Presented in International Scientific Meetings (Proceedings)
C1. Ulu M, Unal ZB, Etoz OA. “Management of a Patient with Papillon-Lefevre Syndrome with Short Dental Implants: A Case Report”, 3rd International Congress of the Oral and Maxillofacial Surgery Society, Antalya, Turkey 2009 (Poster)
C2. Unal ZB, Ulu M, Pala K, Etoz OA. “Immediate Tooth Transplantation Following Cyst Enucleation: A Case Report”, 3rd International Congress of the Oral and Maxillofacial Surgery Society, Antalya, Turkey, 2009 (Poster)
C3. Unal B, Etöz O, Kılıç E, Alkan A. Bishosphonate Related Osteonecrosis of the Jaws: Case Series. 4th AÇBİD International Oral and Maxillofacial Surgery Society Congress. P33.26-30 May 2010, Antalya, Turkey (Oral)
C4. Etöz OA, Demetoğlu D, Gönen ZB, Şekerci AE, Alkan A. An unusual size of mandibular osteoma. 5th AÇBİD International Oral and Maxillofacial Surgery Society Congress and 2nd BAMFS Congress 25-29 May 2011, Antalya, Turkey (Oral)
C5. Çelebi N, Gönen ZB, Kılıç E, Etöz O, Alkan A. “Maxillary sinus floor augmentation in patients with maxillary sinus pseudocyst: case report”. 5th AÇBİD International Oral and Maxillofacial Surgery Society Congress and 2nd BAMFS Congress, sayfa 33, Antalya, Turkey, 25-29 May 2011 (Oral)
C6. Etöz OA, Akçay H, Gönen ZB, Özdamar S, Avunduk MC, Alkan A. Evaluation of the effect of resveratrol on newly formed bone in distraction osteogenesis. 5th AÇBİD International Oral and Maxillofacial Surgery Society Congress and 2nd BAMFS Congress 25-29 Mayıs 2011, Antalya, Turkey (Oral)
C7. Gönen ZB, O. Etöz, A. Alkan. Oral leukoplakia associated to amalgam: healing after replacing amalgam restorations 5th AÇBİD International Oral and Maxillofacial Surgery Society Congress and 2nd BAMFS Congress 25-29 Mayıs 2011, Antalya, Turkey (Poster)
C8. Gönen ZB, Özcan S, Toprak G, Dabanlı D, Şahin FS. Stem cell isolation from human exfoliated deciduous teeth (SHED).1st International Conference/ Workshop on Stem Cell Research and Applications. 7-9 October 2011, Kayseri, TURKEY (Poster)
C9. Toprak G, Özcan S, Gönen ZB, Dabanlı D, Şahin FS. Rabbit Dental Pulp Stem Cell Cultivation. 1st International Conference/ Workshop on Stem Cell Research and Applications. 7-9 October 2011, Kayseri, Turkey (Poster)
C10. Çelebi N, Demirbaş AE, Gönen ZB, Topan C, Alkan A, Kılıç E, Etöz OA. “Is Mandibular Anterior Area a Safe Zone for Implant Placement?’’. 6th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), sayfa 152, Antalya, Turkey, 30 May-3 June 2012 (Poster)
C11. Gönen ZB, Demirbaş AE, Çelebi N, Etöz OA, Alkan A. “Conservative Treatment of Unicystic Ameloblastoma: Report of Two Cases’’. 6th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), sayfa 161, Antalya, Turkey, 30 May-3 June 2012 (Poster)
C12. O.A. Etöz, U. Demetoğlu, Z.B. Gönen, A. Alkan. ‘’Nasal Tooth: Treatment with Transcystic Approach’’, 6th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), Antalya, Turkey, 154, 2012. (Poster)
C13. Etöz, U. Demetoğlu, Z.B. Gönen, E. Soylu, A. Alkan. ‘’Surgical Treatment of Laterally Displaced Post-Traumatic Temporomandibular Joint Ankylosis’’, 6th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), Antalya, Turkey, 77, 2012. (Oral)
C14. O.A. Etöz, Z.B. Gönen, U. Demetoğlu, A. Alkan. ‘’Treatment of Pathological Fracture in A Patient with Bisphosphonate Related Osteonecrosis of the Mandible’’, 6th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), Antalya, Turkey, 114, 2012. (Poster)
C15. Çelebi N, Doğan S, Gönen ZB, Kolçakoğlu KS, Alkan A. “Retrospective analyses of maximum mouth opening in children”. 7th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), sayfa 128, Antalya, Turkey, 29 May-2 June 2013 (Poster)
C16. Kütük N, Baş B, Soylu E, Gönen ZB, Yilmaz C, Balcioğlu E, Özdamar S, Alkan A. “Effect of platelet rich plasma (PRP) on fibrocartilage, hyaline cartilage and bone repair in temporomandibular joint”. 7th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), sayfa 40, Antalya, Turkey, 29 May-2 June 2013 (Oral)
C17. Kütük N, Gönen ZB, Demirbaş AE, Yaşar MT, Alkan A. Retrospective Analysis of Neurosensory Disturbances Related to Dental Implant Placement in the Interforaminal Region. 7th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), sayfa 119, Antalya, Turkey, 29 May-2 June 2013 (Poster)
C18. Demirbaş AE, Çolpak HA, Gönen ZB, Kütük N, Alkan A. “A Retrospective Analysis of Traumatic Bone Cyst of the Jaws”. 7th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), sayfa 119, Antalya, Turkey, 29 May-2 June (Poster)
C19. Gönen ZB, Yılmaz C, Kütük N, Alkan A. Unilateral Facial Nerve Paralysis Caused by Dental Infection. 7th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD), sayfa 121, Antalya, Turkey, 29 May-2 June (Poster)
C20. Kütük N, Demirbaş AE, Topan C, Gönen ZB, Alkan A. Neurosensory disturbances related to dental implant placement in the posterior mandible. 7th International Congress of Oral and Maxillofacial Surgery Society (AÇBİD) sayfa 111. Antalya, TÜRKİYE, 29 May-2 June (Poster)
C21. Gönen ZB, E. Kılıç, A. Alkan. Removal of an implant cover cap accidentaly displaced into the mandibular canal. Ağız ve Çene-Yüz Cerrahisi Birliği Derneği 6. Uluslararası Kongresi, 29 May-2 June; Antalya, Turkey (Poster)
C22. Gonen ZB, Ekizer A, Demirci S, Dogan A, Sardogan A, Şahin F, Alkan A. Apical Papilla Stem Cells from Supernumerary Tooth and Comparative Charactarization with Wisdom Tooth. PP-016 AÇBID -BAOMS joint congress in conjuction with 4th Conference of BAMFS, 5-8 November 2014, İstanbul, Turkey (Poster)
C23. Gonen ZB, Bahar D, Salkın H, Ekizer A,Özcan S, Alkan A . Effect of low level laser therapy on viability, apoptosis and senescence of clinical grade adipose derived mesenchymal stem cells. PP-014 AÇBID -BAOMS joint congress in conjuction with 4th Conference of BAMFS, 5-8 November 2014, İstanbul, Turkey (Poster)
C24. Ergen E, Salkın H, Gönen ZB, Özkul Y. “Effect of PRP on human adipose derived mesenchymal stem cells”. 2nd International Congress on Stem Cell and Cellular Therapies, sayfa 162, Antalya, Türkiye, 15-18 Ekim 2015 (Poster)
C25. Özcan S, Acar MB, Alessio N, Galderisi U, Murat A, Mert E, Toprak G, Ömerli F, Öztürk AR, Gönen ZB. “Secretome of naїve senescent mesenchymal stromal cell promotes senesence in ARH-77 myeloma cells: A proteome analysis of changes in secretome composition”. 2nd International Congress on Stem Cell and Cellular Therapies, p 162, Antalya, Türkiye, 15-18 Ekim 2015 (Poster)
C26. Salkın H, Gönen ZB, Bahar D, Taheri S, Özcan S, Kütük N. “TGF-β1 transfection and PRP on chondrogenic differentiation of DP-MSCs”. 2nd International Congress on Stem Cell and Cellular Therapies, sayfa 192, Antalya, Türkiye, 15-18 Ekim 2015 (Poster)
C27. Gönen ZB, Salkın H, Özcan S, Bahar D, Çetin M. “The optimal electroporation parameters for rabbit dental pulp MSCs”. 2nd International Congress on Stem Cell and Cellular Therapies, sayfa 193, Antalya, Türkiye, 15-18 Ekim 2015 (Poster)
C28. Gönen ZB, Bahar D, Taheri S, Salkın H, Ekizer A, Korkmaz K, Çetin M. “Effect of low-level laser therapy on adipose derived hMSCs”. 2nd International Congress on Stem Cell and Cellular Therapies, sayfa 194, Antalya, Türkiye, 15-18 Ekim 2015 (Poster)
C29. Bolat İE, Yazan M, Kaman S, Gonen ZB, Koçyiğit İD, Atıl F, Tekin U, Süer BT, Alkan A. Evaluation of the Effect of Photoionization on Dental İmplant Osseointegration: Experimental Study, ACBID 2015, 9th International Congress, 27-31 Mayıs Antalya-Türkiye. OP-048 (Oral)
C30. Gonen ZB, Dabanli D, Salkin H, Zararsiz G, Dogruel F, Cetin M, “Evaluation of the Effect of Ankaferd on Dental Pulp Derived Mesenchymal Stem Cells and Gingival Fibroblasts”, pp-286 ACBID 2015, 9th International Congress, 27-31 Mayıs Antalya-TÜRKİYE (poster)
C31. Gonen ZB, Dogruel F, Kaynar LG, Asan C, Çetin M. Short-term Danazol Prophylaxis of Hereditary Angioedema for Dental Implant Treatment: Case Report. pp-273 ACBID 2015, 9th International Congress, 27-31 Mayıs Antalya-TÜRKİYE (poster)
C32. Gonen ZB, Asan C, Topan C, Etöz O, Alkan A. Bisphosphonate Related Osteonecrosis of the Mandible Associated with Dental Implants. pp-240 ACBID 2015, 9th International Congress, 27-31 May Antalya-TURKEY (poster)
C33. Dogruel F, Gonen ZB, Canpolat D, Zararsız G, Alkan A. Evaluation of the Correlation between N/L Ratio, MPV and Prognosis of Patient with Severe Dental Infection. pp-268 ACBID 2015, 9th International Congress, 27-31 Mayıs Antalya-TURKEY (poster)
C34. Gonen ZB, Asan C, Şekerci AE, Zararsiz G, Alkan A. Evaluation of Radiologic Changes in Cone Beam CT Images in Bisphosphoante Related Osteonecrosis of the Jaws pp-256 ACBID 2015, 9th International Congress, 27-31 Mayıs Antalya-TÜRKİYE (poster)
C35. Gönen ZB, Soylu E, Dinç G, Bulut N, Kılıç H. Is The Preparation and Application of PRF Safe in Standard Local Operating Room Air? A Prospective Study. 10 th International ACBID Congress, 10-15May 2016, Antalya, Turkey, p 45 (ORAL)
C36. Gönen ZB, Asan C, Bahar D, Salkın H, Balcıoglu E, Ozdamar S. Exosomes Secreted from Dental Pulp Mesenchymal Stem Cells Promote Repair and Regeneration of Temporomandibular Joint in Osteoarthritis. 10 th International ACBID Congress, 10-15May 2016, Antalya, Turkey, p 74 (ORAL)
C37. Mercan U, Gönen ZB, Salkın H, Yalçın Ulker GM, Meral DG. Comparison of the Effect of Postoperative Care Agents on Human Gingival Fibroblasts. 10 th International ACBID Congress, 10-15May 2016, Antalya, Turkey, p 20 (ORAL)
C38. Gönen ZB, Yilmaz Asan C, Dogruel F, Bozkurt S, Bayram F. Evaluation of Temporomandibular Joint Structures in Acromegaly Patients on Cone Beam Computed Tomography Images. 10 th International ACBID Congress, 10-15May 2016, Antalya, Turkey, p 94 (Poster)
C39. Yilmaz Asan C, Gönen ZB, Akkoyun EF, Alkan A. Maxillary Sinus Volumes and Mucosal Thickness of the Patients with Bisphosphonate Related Osteonecrosis of the Jaws. 10 th International ACBID Congress, 10-15May 2016, Antalya, Turkey, p 89 (Poster)
C40. Gonen ZB, Soylu E. Awareness and Knowledge Level of Dentists in Turkey on BRONJ: A Survey Based Study. Turkish Dental Association 23. International Dental Congress, 21-24 September 2017 (oral)
C41. Gonen ZB, Bilge S, Onder ME, Etöz O, Bahar D, Alkan A. Preventive effect of dental pulp-derived mesenchymal stem cells in experimental medication-related osteonecrosis of the jaw”, 23. International Conference on Oral and Maxillofacial Surgery, 31 Mart-3 Nisan 2017, Hong Kong (oral presentation)
C42. Gonen ZB, Alkan A, Uysal T, Ucar F, Kutuk N, Ekizer A, Tasdemir Z. Evaluation of Vestibular Bone Thickness in Class I Malocclusion Treatment with Corticotomy Assisted Rapid Orthodontics. 22-25 August 2014, 11th Asian Congress on Oral and Maxillofacial Surgery, Xian, China (Oral Presentation)
C43. Saraymen B, Karaman I, Gonen ZB, Dogruel F, Koker Y. The Percentages of Endothelial Progenitor Cell with Expression of CD133+, CD 309+, CD34+ at 6. Hour after both Artery Laceration and 20 years tooth Extraction Procedure in Peripheral Blood Samples. 4TH European Congress of Immunology, 6-9 September, Vienna, Austria, 2015 (Poster)
C44. Gonen ZB, Soylu E, Salkın H. The effect of thymoquinone on mesenchymal stem cells from apical papilla. TAOMS (Turkish Association of Oral and Maxillofacial Surgery) 25. International Scientific Congress. 13-17 May 2018, KYRENIA, CYPRUS
C45. Gonen ZB, Dinc G, Bahar D. Assessment of Antimicrobial Effect of Exosomes Secreted from Dental Pulp Mesenchymal Stem Cells. International Association of Oral and Maxillofacial Surgery (IAOMS) in conjunction with 12. ACBID Congress, 9-13 May 2018, Antalya, Turkey
D. Reports Presented in National Scientific Meetings and Published in Proceedings:
D1. Çelebi N, Soylu E, Gönen ZB, Kılıç E, Etöz OA, Alkan A. Retrospective Evaluation of Dental Implant Success: Three to Five Years Follow Up. 5. ITI Turkish Congress, İstanbul, Turkey, 21-22 Mayıs 2011, (Oral)
D2. Ekizer A, Bozkurt S, Gönen ZB, Ekizer E. Evaluation of the Airway in different malocclusion types. 13.Turkish Orthodontics Congress .3-5 November 2013, İstanbul, Turkey (Poster)
D3. Ekizer A, Gönen ZB, Altınpulluk MÖ, Uysal T, Alkan A. The effect of corticotomy on treatment time in Class I Malocllusion 13. Turkish Orthodontics Congress. 3-5 November 2013, İstanbul, Turkey (Poster)
D4. Doğruel F, Gönen ZB, Canpolat DG, Ocak H, Bayram F. Evaluation the level of Vitamin D in Dental Faculty. 37. Turkish Endocrinology and Metabolism Disorders Congress, page 387, Antalya, Turkey, 6-10 May 2015 (Poster)
D5. Canpolat DG, Gönen ZB, Doğruel F, Şengül İ, Yıldız K, “Determination of Cardiopulmonary Resuscitation Knowledge Level of Dentists.” Turkish Association of Anesthesiology and Reanimation 49. National Congress, s1, Antalya, Turkey, 2-6 Aralık 2015 (oral p)
D6. Gönen ZB, Canpolat DG, Yay A, Bahar D, Kütük N, Çolpak H, Yalçın B, Alkan A. “Effect of dental pulp derived mesenchymal stem cells on mental nerve repair”. Turkish Association of Anesthesiology and Reanimation 49. National Congress, p 39, Antalya, Turkey, 2-6 December 2015 (Poster)
D7. Canpolat DG, Doğruel F, Gönen ZB, Yılmaz C, Zararsız G, Alkan A. “The role of PLT, MPV, MPV/PLT ratio in prediction of PONV in children after deep sedation”. Turkish Association of Anesthesiology and Reanimation 49. National Congress, p 761, Antalya, Turkey, 2-6 December 2015 (Poster)
D8. Canpolat DG, Gönen ZB, Durdu T. “Evaluation of Approaches of the Dentists to General Anesthesia in the Clinical Practice.” Turkish Association of Anesthesiology and Reanimation 49. National Congress, p 851, Antalya, Turkey, 2-6 December 2015 (Poster)
D9. Bayram F, Gönen ZB, Doğruel F, Öztürk S, Şenol S, Kurtsoy A. Investigation of the changes in craniomandibular bony changes in new diagnosed acromegaly patients: cone beam CT study. 38. Turkish Endocrinology and Metabolic Diseases Congress, sayfa 357, Antalya, Turkey, 11-15 Mayıs 2016 & 2. National Lipid Symposium 14 May 2016 (Poster)
D10. Geçor O, Polat S, Acar AH, Gonen ZB, Keleş A, Ataç MS. Investigaton of different biomaterials on perimplant defect healing. 22nd Turkish Association of Oral and Maxillofacial Surgery, TAOMS 2015 19–23 May 2015.OP-05 Bodrum, Muğla, Turkey (oral p)
D11. Soylu E, Gönen ZB, Alkan A. ‘’A New Detection Method for Submerged Implants: Oral Tattoo", 22nd Turkish Association of Oral and Maxillofacial Surgery, TAOMS 2015 19–23 May 2015.PP 161 Bodrum, Muğla, Turkey (Poster)
COURSES ATTENDED
- Strasbourg Osteosynthesis Research Group (S.O.R.G.), Live surgery course on preprosthetic reconstructive Surgery, 13-14 Jan 2011, İstanbul, Turkey
- AOCMF Principles Course, 11-13 Feb 2011 İstanbul, Turkey
- AOCMF ‘TMJ Advanved Techniques’, 21-22 Nov 2013, Leipzig, Germany
- Temporomandibular Joint Arthroscopy’ masterclass and Hands on Cadaver Workshop, 29 May 2013, Akdeniz University Anatomy Institute, Antalya, Turkey
- ‘Zygomatic Implants’, 3 Jun 2012, Antalya, Turkey
- ‘Use of OSMED in Oral and Maxillofacial Surgery’ Course, 2012, Antalya, Turkey
- ‘Hands on orthognathic treatment planning course ‘Course, 1 Jun 2013, Antalya
- ‘Botox and Fillers’ course, 30 May 2012, Antalya, Turkey
- ‘Orthognathic Surgery Fixation Methods Hands On Course ', Current Treatments in Jaw and Face Deformations Symposium, 21-24 Feb 2013, Kayseri, Turkey
- 2th ‘Basics of Mammalian Cell Culture Course’, 1-3 Dec 2010, Kayseri, Turkey
- ‘The role of Arthroscopy in TMJ Surgery’ Course ,22 Apr 2009, Antalya, Turkey
- Experimental Animal Use Certificate, 18-28 May 2009, Kayseri, Turkey
- Occupational Health and Safety Training, Alp İş Academy Occupational Health and Safety Center, 13, Aug 2013, Turkey
- EU Directive on Human Tissues and Cells Laboratory Aspects, 22-24 Dec 2014, Ankara Turkey
- GMP Certification: Stem Cell cGMP Laboratory Quality Assurance System and Production, Erciyes University Genome and Stem Cell Center, 1 Jan-1 Sep 2014, Kayseri, Turkey
- Theoretical and Applied Tissue Engineering Summer School, Tissue Engineering, Hacettepe University, Course, 26.09.2016 -30 Sep 2016, Ankara, Turkey
- 3th International stem cell course: Innovative Cellular Treatment Course, May 19-22, 2016 Antalya, Turkey
- Applied Biostatistics, Turcosa Analytical Solutions. 7 Dec 2015 – 22 Jan 2016, Kayseri Turkey
- Applied Western Blotting Course Gene Era, Biorad, 26 May, 2016 Kayseri, Turkey
- Education Skills Course, Erciyes University, Medical Education A.D., 28 Nov-02 Dec 2016, Kayseri Turkey
- Practical Microvascular Course, Poole Hospital NHS Trust, 24 -28 Jul 2017, United Kingdom
Memberships in Scientific Organizations
- Oral and Maxillofacial Surgeons Society of Turkey (ACBID)
- European Association for Cranio Maxillo Facial Surgery (EACMFS)
- International Association of Oral and Maxillofacial Surgeons (IAOMS)
- International Team of Implantology (ITI)
SUPERVISED THESIS
Doctorate
Süheyb BİLGE, Radiological and Biochemical Evaluation of the Efficiency of Stem Cell Applications in Experimental Bisphosphonate Osteonecrosis of the Jaw, Erciyes University / Institute of Health Sciences / Department of Oral and Maxillofacial Surgery, 2016 Completed (Supervisor)
Dilek BAHAR, Investigation of the Effect of Umbilical Cord derived Mesenchymal Stem Cell Exosomes -Chitosan / Hydroxyapatite Biomaterials on the Bone Regeneration, Institute of Sciences, Biology Department, 2019 (Assistant Supervisor)
Master of Science
Buket Banu ÖZKAN, Investigation of Clinically Applicable Production Conditions of Platelet Rich Fibrin-Derived Mesenchymal Stem Cells. Health Sciences Institute, Department of Stem Cell Sciences, 2019 (Supervisor)
Nur Seda ŞAHİN, Evaluation of the Effect of Hypoxic Medium on Microvesicle Activity. Health Sciences Institute, Department of Stem Cell Sciences. 2019 (Supervisor)
Ravza Tosunbayraktar, Investigation of Adipose Tissue Matrix Decellularization Methods, Health Sciences Institute, Department of Stem Cell Sciences. 2020 (Supervisor)