Oscar Kuang-Sheng Lee, MD, PhD, MSc, Prof.
Orthopaedic Surgeon
EDUCATION
CURRENT POSITIONS
RESEARCH INTERESTS
Stem cell biology, Musculoskeletal research, Tissue engineering
Professor Oscar Lee is an orthopedic surgeon and a faculty member in the Institute of Clinical Medicine, NYCU. His major research theme is plasticity and application of Mesenchymal stem cells (MSCs), in particular, the development of new application of MSCs to treat diseases that currently lack cures. Over the years, Professor Lee and his research team reported the successful isolation of multipotent MSCs from various human tissues and demonstrated their therapeutic potentials for various disease treatments. They also developed non-disruptive and label free approaches to detect the extent of maturation and mineralization level during osteogenic differentiation in real-time. Professor Lee devoted research efforts to the studies of micro-environmental cues and biophysical effects, such as matrix stiffness and shear stress, on stem cell physiology as well as to the development of bio-inspired materials for lineage-directed differentiation. In recent years, Professor Lee has also made great efforts studying the role of hMSCs in regulating hematopoietic stem cell fate and their therapeutic potential to treat lupus nephritis, spinocerebellar ataxia and diabetes in different animal models. Professor Lee has published more than 100 peer-reviewed articles in leading journals such as Cell, Nature Biology, Gastroenterology, Hepatology and Blood. Professor Lee also has contribution in education and training, and started serving as Deputy Chief Executive Officer of National Yang-Ming University EMBA Program since 2017.
- 1993 MD, School of Medicine, National Yang-Ming University
- 1999 MSc, Institute of Orthopaedics, University College London
- 2002 PhD, Centre for Biomedical Engineering, University College London
- 2008 EMBA, National Chengchi University, Taiwan
CURRENT POSITIONS
- Vice Superintendent, China Medical University Hospital
- Chair Professor, Institute of Clinical Medicine, National Yang Ming Chiao Tung University
- Director, Stem Cell Research Centre, National Yang Ming Chiao Tung University
- Professor, Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital
- Adjunct Professor, Institute of Biophotonics, Institute of Biomedical Engineering, Institute of Hospital and Health Care Administration, National Yang Ming Chiao Tung University
- Adjunct Research Fellow, Institute of Cellular and System Medicine, National Health Research Institutes, Taiwan
RESEARCH INTERESTS
Stem cell biology, Musculoskeletal research, Tissue engineering
Professor Oscar Lee is an orthopedic surgeon and a faculty member in the Institute of Clinical Medicine, NYCU. His major research theme is plasticity and application of Mesenchymal stem cells (MSCs), in particular, the development of new application of MSCs to treat diseases that currently lack cures. Over the years, Professor Lee and his research team reported the successful isolation of multipotent MSCs from various human tissues and demonstrated their therapeutic potentials for various disease treatments. They also developed non-disruptive and label free approaches to detect the extent of maturation and mineralization level during osteogenic differentiation in real-time. Professor Lee devoted research efforts to the studies of micro-environmental cues and biophysical effects, such as matrix stiffness and shear stress, on stem cell physiology as well as to the development of bio-inspired materials for lineage-directed differentiation. In recent years, Professor Lee has also made great efforts studying the role of hMSCs in regulating hematopoietic stem cell fate and their therapeutic potential to treat lupus nephritis, spinocerebellar ataxia and diabetes in different animal models. Professor Lee has published more than 100 peer-reviewed articles in leading journals such as Cell, Nature Biology, Gastroenterology, Hepatology and Blood. Professor Lee also has contribution in education and training, and started serving as Deputy Chief Executive Officer of National Yang-Ming University EMBA Program since 2017.